Institute for Medical Education and Research, Madelyn Trupkin Herzfeld, IMER, imer, imier, Miami, Florida, Nursing CE's, Nursing contact hours, nursing education, continuing education, medical research and education, Oncology, Postgraduate credit, oncology nurses, nurses, symposia, symposium, online educational credit, Breast Cancer, Cancer, cancer, breast cancer, colorectal cancer, Colorectal Cancer, Targeting EGFR, EGFR Inhibitors, egfr inhibitors, head and neck cancer, Anti-VEGF, VEGF Inhibitors, vegf inhibitors, lung cancer, head cancer, CINV, cinv, Chemotherapy Induced Nausea & Vomiting, chemotherapy, nausea, vomiting, mucositis, cancer pain, chronic pain  
Institute for Medical Education and Research, Madelyn Trupkin Herzfeld, IMER, imer, imier, Miami, Florida, Nursing CE's, Nursing contact hours, nursing education, continuing education, medical research and education, Oncology, Postgraduate credit, oncolog
   
  CURRENT TOPICS IN CANCER: TARGETING EGFR
Current Topics in Cancer Oncology Nurses: Targeting EGFR

Volume 2, Number 1 Spring 2005
Release date: May, 2005 Expiration date: May 2006

Introduction
The treatment of patients with cancer is complex and a multitude of treatment strategies are employed, either individually or in combination. When possible, surgery is performed to remove known tumor masses. Rapidly dividing tumor cells are then destroyed locally by radiation therapy and systemically by chemotherapy. Hormonal therapy is used to inhibit the growth of hormonedependent tumors such as breast cancer or prostate cancer. In recent years, targeted therapies have been added to the armamentarium of cancer treatments. These novel agents inhibit specific molecules or cellular processes that support tumor growt and progression. Because these drugs are directed against specific molecules or cellular processes, patients are subjected to fewer of the generalized toxic effects of cytotoxic therapies that indiscriminantly attack a variety of cell types. For example, the use of targeted therapies alone is not generally associated with the common side effects of chemotherapy and radiation such as hair loss and oral mucositis. When used in combination with chemotherapy or radiation, targeted therapies are well tolerated and can enhance patient response.

The first molecule to be identified as a potential target for cancer therapy was the epidermal growth factor receptor (EGFR), which plays an important role in cell function, cell growth, and cellular interactions. Three targeted therapies directed against the EGFR have recently been approved for the treatment of colorectal or lung cancer. It is critical for oncology nurses to understand the safe administration and unique mechanisms of action and side effect profiles of EGFR inhibitors as they continue to be integrated into oncology clinical practice.

TARGET AUDIENCE
This activity has been designed to meet the educational needs of oncology registered nurses.

PROGRAM OVERVIEW
The epidermal growth factor receptor (EGFR) pathway plays a critical role in the processes involved in tumor growth and progression and has been identified as a potential target for cancer therapy. In recent years, three EGFR inhibitors were approved for the treatment of colorectal and non-small cell lung cancer, and many others are under investigation for the treatment of solid tumors. Understanding the mechanisms of action of EGFR inhibitors, as well as their administration guidelines and side effect profiles, is important for optimal care of patients receiving these novel therapies.

PURPOSE
Provide education to oncology nurses on the role of the EGFR pathway in tumor growth and progression, mechanisms of action of agents targeting EGFR, current indications for EGFR inhibitors in clinical practice, and their administration guidelines and side effect profiles.

EDUCATIONAL OBJECTIVES

Upon completion of this program, participants should be able to:

  • Discuss the role of EGFR in carcinogenesis and tumor progression
  • Identify the current indications for EGFR inhibitors
  • Describe nursing administration guidelines for EGFR inhibitors
  • List side effects of the EGFR inhibitors

FACULTY
Debra Wujcik, RN, MSN, AOCN®
Director, Clinical Trials Training and
Outreach
Vanderbilt-Ingram Cancer Center

ACCREDITATION STATEMENTS
This educational activity for 1.8 contact hours is provided by the Postgraduate Institute for Medicine. Postgraduate Institute for Medicine is an approved provider of continuing education by the Colorado Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.

CALIFORNIA BOARD OF REGISTERED NURSING
The Postgraduate Institute for Medicine is approved by the California Board of Registered Nursing, Provider Number 13485 for 1.8 contact hours.

FACULTY DISCLOSURE STATEMENTS
Postgraduate Institute for Medicine has a conflict of interest policy that requires course faculty to disclose any real or apparent commercial financial affiliations related to the content of their presentations/materials. It is not assumed that these financial interests or affiliations will have an adverse impact on faculty presentations; they are simply noted here to fully inform participants.

Debra Wujcik, RN, MSN, AOCN®, has a financial interest/relationship or affiliation in the form of: Speakers’ Bureau, Amgen Inc., Merck & Co., Inc., Bristol-Myers Squibb Company; Nurse Advisory Board, Bristol-Myers Squibb Company and ImClome Systems Incorporated.

METHOD OF PARTICIPATION
There are no fees for participating and receiving CNE credit for this activity. During the period May, 2005 through May, 2006, participants must: 1) read the learning objectives and faculty disclosures; 2) study the educational activity; 3) complete the post-test by recording the best answer to each question in the answer key on the evaluation form; 4) complete the evaluation form; and 5) mail or fax the evaluation form and post-test to Postgraduate Institute for Medicine.

A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed post-test with a score of 70% or better. Your statement of credit will be mailed to you within three weeks.

MEDIA
Printed Newsletter

DISCLOSURE OF UNLABELED USE
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Postgraduate Institute for Medicine (PIM), Institute for Medical Education & Research, Inc. (IMER), Bristol-Myers Squibb Company, and ImClone Systems Incorporated do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of PIM, IMER, Bristol-Myers Squibb Company, or ImClone Systems Incorporated. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

DISCLAIMER
Participants have an implied to use the newly acquired enhance patient outcomes professional development. presented in this activity serve as a guideline for management. Any procedures, courses of diagnosis or or suggested in this activity used by clinicians without patients’ conditions and contraindications on dangers in applicable manufacturer’s information, and comparison of other authorities.

This activity is supported by an unrestricted educational grant from Bristol-Myers Squibb Company and ImClone Systems Incorporated.

Colorectal Cancer
Page 1

Cancer Pain
Cancer Pain
  COLON CANCER
Co-sponsored by:

imer

pim

This program is supported by an unrestricted educational grant from Bristol-Myers Squibb Company and ImClone Systems Incorporated.

 
   

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